Brad Barritt, Tom Wood, Geoff Parling and Kyle Eastmond are ruled out of England's Six Nations opener against Wales on 6 February.
Up to 137 jobs are under threat as part of plans to close three Tesco stores across Wales.
Greek financial markets were in turmoil on Wednesday with investors fearing the new anti-bailout government was determined to defy its international creditors.
Spending on care for people aged 65 and over has fallen by a fifth in England over the last 10 years, an analysis by the BBC shows.
China's biggest internet retailer, Alibaba, is involved in a harshly worded spat with one of the country's regulators in a highly unusual public clash.
Former Barcelona and Real Madrid forward Luis Figo aims to challenge Sepp Blatter for Fifa's top job.
Perth Scorchers defy Brett Lee's heroics to beat Sydney Sixers off the final ball and win the Big Bash.
Sri Lanka's new president reinstates Chief Justice Shirani Bandaranayake two years after she was controversially sacked by his predecessor.
Seattle Seahawks' Marshawn Lynch says the same thing 29 times as he reluctantly fulfils his Super Bowl media duty.
Tesco names the 43 stores it is closing across the country, a move that will see 2,000 staff lose their jobs.
An Indian child-murderer convicted in a case dubbed "the house of horrors" escapes execution, as a court commutes his sentence to life in prison.
Images from around the world: 28 January
Jordan says it is ready to free an Iraqi on death row in return for a pilot facing execution by Islamic State alongside a Japanese hostage.
Sale Sharks and former England winger Mark Cueto announces he will end his playing career at the end of the season.
Schools at the centre of the Trojan Horse allegations in Birmingham are struggling to recruit staff, the Chief Inspector of Schools has told MPs.
Tesco is to close three shops in east Belfast and Ballymena, putting more than 150 jobs at risk
MPs hear evidence on the press briefing of Financial Conduct Authority information.
A drug costing millions of pounds per patient has been given the green light for use on the NHS by the medicines watchdog NICE.
What Saudis really think about Michelle Obama's bare head
Suspected hackers briefly hijack a popular Christian radio station in Kenya, and play Islamic verses before it went off air.